Why is "Adenine" trending?

Search Interest Perspective

• Precise, minimally evolved adenine base editors generated through mutation reversion analysis - Nature
• ACSH Explains: Nicotinamide adenine dinucleotide (NAD) - American Council on Science and Health
• RNA inosine sensor-guided TadA mutational scanning for toxicity minimization of adenine base editors - ScienceDirect.com
• Programmable adenine base editing in cyanobacteria using an engineered TadA-Cas9 fusion - Wiley Online Library
• Engineering a high-fidelity adenine base editor for safe in vivo gene therapy - EurekAlert!
• Adenine DNA methylation associated with transcriptionally permissive chromatin is widespread across eukaryotes - Nature
• NAD plays a key role in energy metabolism - Lifespan Research Institute
• Hybrid Guide RNAs Improve Adenine Base Editing for Rare Disease Therapy - GenomeWeb
• Altered nicotinamide adenine dinucleotide metabolism drives cartilage degeneration and osteoarthritis - Wiley Online Library
• Intravitreal adenine base editing of RS1 improves vision in a preclinical mouse model of retinoschisis - ScienceDirect.com
• Improved specificity and efficiency of in vivo adenine base editing therapies with hybrid guide RNAs - Nature
• A motif preferred adenine base editor with minimal bystander and off-targets editing - Nature
• Late-stage adenine N6-alkylation of nucleos(t)ides and oligonucleotides via photoredox and copper co-catalytic decarboxylative C(sp3)–N coupling - Nature
• Protein-nucleic acid language model-assisted design of precise and compact adenine base editor - Nature
• Unveiling a pervasive DNA adenine methylation regulatory network in the early-diverging fungus Rhizopus microsporus - Nature
• Improving adenine base editor precision with directed evolution and extended guide RNAs - Nature
• Adenine DNA methylation is an ancestral and widespread mark in eukaryotes - Nature
• Gavage versus dietary adenine administration is more effective for the female mouse model of chronic kidney disease - Nature
• PAM-flexible adenine base editing rescues hearing loss in a humanized MPZL2 mouse model harboring an East Asian founder mutation - Nature
• Mechanism for the substrate recognition by a eukaryotic DNA N - Nature
• 5 NAD Supplements Benefits, Backed by Science - Health: Trusted and Empathetic Health and Wellness Information
• Curing the bystander effect: A new base editing tool minimizes unwanted edits to DNA - EurekAlert!
• Characterization of the Nicotinamide Adenine Dinucleotide Biosynthesis Pathway and Regulatory Mechanisms in Streptococcus mutans - Wiley
• Quantification of Adenine Residues in the PolyA Tail of Oligonucleotides Using Raman Spectroscopy - Spectroscopy Online
• Nicotinamide adenine dinucleotide fluorescence monitoring as a potential tool for the microvascular and mitochondrial function assessment in heart failure | Parzuchowska | Cardiology Journal - Via Medica Journals
• Longevity: Can NAD supplements really slow down aging? - Medical News Today
• Artificial Seawater Models Affect Sorption of Adenine and Related Molecules Sorption onto Montmorillonite: Implications for Early Mars and Earth Oceans - astrobiology.com
• Nicotinamide Adenine Dinucleotide Nad Market Analysis - openPR.com
• Nicotinamide Adenine Dinucleotide Market Evolution | - openPR.com
• Novel adenine base editor shows superior precision - CRISPR Medicine News
• NAD+ Supplements: Can They Really Slow Down Aging? - Cleveland Clinic Health Essentials
• Engineering Adenine Deaminase TadA for Precise and PAM-Flexible Point Mutagenesis and Gradient-Tuning Endogenous Protein Design - Wiley
• Revvity and Profluent to launch AI-enhanced adenine deaminase pin-point base editing systems - BioSpectrum Asia
• Chemical evolution: The mechanism of the formation of adenine under prebiotic conditions - PNAS
• A split and inducible adenine base editor for precise in vivo base editing - Nature
• An adenine base editor variant expands context compatibility - Nature
• Introducing the “other” type of DNA methylation - Science | AAAS
• India Nicotinamide Adenine Dinucleotide (NAD) Products Market Size & Outlook, 2033 - Grand View Research
• Improving adenine base editing precision by enlarging the recognition domain of CRISPR-Cas9 - Nature
• Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryos - Nature
• ABE-ultramax for high-efficiency biallelic adenine base editing in zebrafish - Nature
• Symmetric and asymmetric DNA N6-adenine methylation regulates different biological responses in Mucorales - Nature
• Precision genome editing using cytosine and adenine base editors in mammalian cells - Nature
• Adenine base editing efficiently restores the function of Fanconi anemia hematopoietic stem and progenitor cells - Nature
• Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity - Nature
• Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity - Nature
• Synthetic syntrophy for adenine nucleotide cross-feeding between metabolically active nanoreactors - Nature
• Engineering a precise adenine base editor with minimal bystander editing - Nature
• Human cell based directed evolution of adenine base editors with improved efficiency - Nature
• Directed evolution of adenine base editors with increased activity and therapeutic application - Nature
• The United States Nicotinamide Adenine Dinucleotide (NAD) Products Market Size & Outlook, 2033 - Grand View Research
• Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing - Nature
• Leveraging base excision repair for efficient adenine base editing of mitochondrial DNA - Nature
• Hepatitis C virus RNA is 5′-capped with flavin adenine dinucleotide - Nature
• Therapeutic adenine base editing of human hematopoietic stem cells - Nature
• Adenine base editors catalyze cytosine conversions in human cells - Nature
• Adenine overload induces ferroptosis in human primary proximal tubular epithelial cells - Nature
• Editorial: Adenine nucleotides in immunity and inflammation - Frontiers
• Excess S -adenosylmethionine inhibits methylation via catabolism to adenine - Nature
• de Mendoza Lab publishes an article in Nature Genetics on the evolution and function of adenine DNA methylation - Queen Mary University of London
• Structural basis of adenine nucleotides regulation and neurodegenerative pathology in ClC-3 exchanger - Nature
• Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope - Nature
• Critical assessment of DNA adenine methylation in eukaryotes using quantitative deconvolution - Science | AAAS
• A widespread pathway for substitution of adenine by diaminopurine in phage genomes - Science | AAAS
• ANZ Nicotinamide Adenine Dinucleotide (NAD) Products Market Size & Outlook, 2033 - Grand View Research
• TadA orthologs enable both cytosine and adenine editing of base editors - Nature
• ABE8e adenine base editor precisely and efficiently corrects a recurrent COL7A1 nonsense mutation - Nature
• UK Nicotinamide Adenine Dinucleotide (NAD) Products Market Size & Outlook, 2033 - Grand View Research
• Improving adenine and dual base editors through introduction of TadA-8e and Rad51DBD - Nature
• Means, mechanisms and consequences of adenine methylation in DNA - Nature
• Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction - Nature
• Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase - PNAS
• The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site - Nature
• How cyanophage S-2L rejects adenine and incorporates 2-aminoadenine to saturate hydrogen bonding in its DNA - Nature
• Herbicide-resistant plants produced by precision adenine base editing in plastid DNA - Nature
• Domain-inlaid Nme2Cas9 adenine base editors with improved activity and targeting scope - Nature
• Structural basis for MTA1c-mediated DNA N6-adenine methylation - Nature
• Docking sites inside Cas9 for adenine base editing diversification and RNA off-target elimination - Nature
• Enterococcus faecalis -derived adenine enhances enterohaemorrhagic Escherichia coli Type 3 Secretion System-dependent virulence - Nature
• Biological roles of adenine methylation in RNA - Nature
• A Cas9 with PAM recognition for adenine dinucleotides - Nature
• DNA methylation on N6-adenine in mammalian embryonic stem cells - Nature
• Sequence-specific prediction of the efficiencies of adenine and cytosine base editors - Nature
• Hypercompact adenine base editors based on a Cas12f variant guided by engineered RNA - Nature
• Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage - Nature
• Programmable A-to-Y base editing by fusing an adenine base editor with an N-methylpurine DNA glycosylase - Nature
• Adenine base editor engineering reduces editing of bystander cytosines - Nature
• Structure-guided engineering of adenine base editor with minimized RNA off-targeting activity - Nature
• Clostridioides difficile specific DNA adenine methyltransferase CamA squeezes and flips adenine out of DNA helix - Nature
• Adenine base editing in an adult mouse model of tyrosinaemia - Nature
• The adenine nucleotide translocase family underlies cardiac ischemia-reperfusion injury through the mitochondrial permeability pore independently of cyclophilin D - Science | AAAS
• Roles of adenine methylation in the physiology of Lacticaseibacillus paracasei - Nature
• The DNA N6-adenine methylation target gene GhMAF1 promotes fiber initiation at the base of Gossypium ovules - Wiley
• Mexico Nicotinamide Adenine Dinucleotide (NAD) Products Market Size & Outlook, 2033 - Grand View Research
• Repurposing an adenine riboswitch into a fluorogenic imaging and sensing tag - Nature
• DNA interstrand cross-links induced by the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine - Nature
• Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses - Nature
• Chromatin profiling using targeted DNA adenine methyltransferase - Nature
• Cytosine and adenine deaminase base-editors induce broad and nonspecific changes in gene expression and splicing - Nature
• Targeting fidelity of adenine and cytosine base editors in mouse embryos - Nature