Why is "Acyclovir" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-03-21 01:13:46
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Acyclovir entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-03-21 and was most recently seen on 2026-03-21.
Wikipedia Overview
Aciclovir, also known as acyclovir, is an antiviral medication. It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. Other uses include the prevention of cytomegalovirus infections following transplant, and severe complications of Epstein–Barr virus infection. It can be taken by mouth, applied as a cream, or injected.
Read more on Wikipedia →Related Topics
Trending Topic Today
Search Interest Perspective
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Limitations of acyclovir and identification of potent HSV antivirals using 3D bioprinted human skin equivalents - Nature
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Alopecia Following Oral Acyclovir for the... : Middle East African Journal of Ophthalmology - Ovid
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Therapeutic Impact of Caffeic Acid Phenethyl Ester and Acyclovir Combination on Human Gingival Fibroblasts (HGF-1) Infected With Herpes Simplex Type 1 ICP0 - Wiley Online Library
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Herpes Simplex Virus Esophagitis in an Immunocompetent Man - Medscape
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Acyclovir-Activated Poison Exon Enables Reversible Gene Expression - Genetic Engineering and Biotechnology News
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Researchers unveil a powerful new gene-switch tool - Cornell Chronicle
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Intractable Hiccups: An Atypical Presentation of... : American Journal of Gastroenterology - Lippincott Home
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Acute Generalized Exanthematous Pustulosis Associated With Acyclovir, Confirmed by Patch Testing - Sage Journals
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Atypical Presentations of Acyclovir-Resistant Herpes Simplex Virus in Immunocompromised Patients: A Case Series - Cureus
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Acyclovir-induced Fixed Drug Eruption in a... : Indian Journal of Paediatric Dermatology - Ovid
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Alzheimer's and the Gut; Long COVID and the Brain; HHS Names Alzheimer's Advisors - MedPage Today
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Treatment of Herpes simplex encephalitis with the helicase-primase inhibitor pritelivir in an immunocompromised patient - Nature
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Antiviral trial ties valacyclovir to faster cognitive decline - Medical Xpress
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Innovative Molecules Starts Phase 2a Trial of Adibelivir for Genital Herpes - The Clinical Trial Vanguard
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Off Patent Cancer Drug Shows Promise for Herpes Simplex 1 - Medical News Bulletin
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Oral Acyclovir Suppression and Neurodevelopment after Neonatal Herpes - NEJM
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Pritelivir Shows Promise for HSV - Medscape
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Characterization and safety evaluation of highly swellable polymeric nanomatrices for enhanced solubility of acyclovir - Nature
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Herpes prophylaxis during pregnancy : Evidence-Based Practice - Ovid
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An industrial procedure for the intestinal permeability enhancement of acyclovir: in-vitro and histological evidence - Nature
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Acyclovir-Induced Nephrotoxicity: A Case Report - Cureus
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Acyclovir Prophylaxis Reduces Oral Mucositis Incidence in HSCT Recipients - Targeted Oncology
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Refractory and/or Resistant Herpes Simplex Virus Mucocutaneous Infections in Adult Transplantation and Cellular Therapy Patients: A Single-Center Experience - Cureus
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Acyclovir-Induced Nephrotoxicity and Neurotoxicity: A Report of Two Cases - Cureus
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Pharmacokinetics of Acyclovir and Its Metabolites in Cerebrospinal Fluid and Systemic Circulation after Administration of High-Dose Valacyclovir in Subjects with Normal and Impaired Renal Function - journals.asm.org
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Pseudoboehmite as a drug delivery system for acyclovir - Nature
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Early Treatment with Prednisolone or Acyclovir in Bell's Palsy - NEJM
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NUDT15 polymorphism influences the metabolism and therapeutic effects of acyclovir and ganciclovir - Nature
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Extravasation of Intravenous Acyclovir in a Patient With Human Herpesvirus 7 Encephalitis: A Case Report - Cureus
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Early Treatment with Prednisolone or Acyclovir in Bell's Palsy - NEJM
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Treatment of Long-Haul COVID Patients With Off-Label Acyclovir - Cureus
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Trigeminal Neuralgia Secondary to Herpes Simplex Virus Type 1 Infection Treated With Oral Acyclovir - Cureus
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Phase 3 trial confirms superior efficacy of oral pritelivir for refractory HSV in immunocompromised patients - European AIDS Treatment Group
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Acyclovir for the Prevention of Recurrent Herpes Simplex Virus Eye Disease - NEJM
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Long-Term Oral Acyclovir for the Prevention of Recurrent Herpetic Uveitis - ARVO Journals
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Thymidine Kinase Mutations Conferring Acyclovir Resistance in Herpes Simplex Type 1 Recombinant Viruses - journals.asm.org
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Acyclovir and Transmission of HIV-1 from Persons Infected with HIV-1 and HSV-2 - NEJM
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Herpes Simplex Virus Resistance to Acyclovir and Penciclovir after Two Decades of Antiviral Therapy - journals.asm.org
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A Dose Too Far: Valacyclovir’s Surprising Side Effect - Cureus
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Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2 - Frontiers
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Rare Disease Drug Alone and in Combination with Acyclovir Shows Promise Against HSV - Inside Precision Medicine
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Recurrent Acyclovir-Resistant Genital Herpes in an Immunocompetent Patient - NEJM
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Patient Care for B Virus - Centers for Disease Control and Prevention | CDC (.gov)
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Efficacy of low-dose zoster prophylaxis in patients undergoing allogeneic hematopoietic cell transplantation - Nature
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IDWeek 2025: pritelivir to address gap in market for HSV infections - Clinical Trials Arena
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Glioblastoma Mimicking Viral Encephalitis Responds to Acyclovir: A Case Series and Literature Review - Frontiers
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Recurrent encephalitis and stroke following cessation of acyclovir prophylaxis in a patient with neonatal herpes simplex virus with RNF213 mutation - Wiley Online Library
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Intravitreal injection of acyclovir causes dose-related retinal toxicity in rabbits - ARVO Journals
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Treating HSV keratitis - EyeWorld
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High-dose aciclovir in CMV infection prophylaxis after allogeneic HSCT: a single-center long-term experience - Nature
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Herpes Helper - Review of Optometry
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A Comparative Study of Intralesional Acyclovir vs Immunotherapy for Treatment of Viral Warts - Cureus
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Acyclovir May Decrease HSV Oropharyngeal Shedding in Medically Ventilated Patients - Contagion Live
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Efficacy, bioavailability, and intracellular delivery of nanoparticle based drug encapsulated carbon for antiviral therapy - Nature
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From HEDS to ZEDS: Managing Herpetic Eye Disease - Review of Optometry
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A Randomized Trial of Acyclovir for 7 Days or 21 Days with and without Prednisolone for Treatment of Acute Herpes Zoster - NEJM
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Neonatal Varicella, Treated With Oral Acyclovir: A Rare and Challenging Case Report in a Limited-Resource Country Like Cambodia - Wiley Online Library
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New strategies against drug resistance to herpes simplex virus - Nature
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Crystalluria from Acyclovir Use - NEJM
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A Continuous Infusion of Acyclovir for Severe Hemorrhagic Varicella - NEJM
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Vidarabine versus Acyclovir Therapy in Herpes Simplex Encephalitis - NEJM
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Acyclovir for Equine Sarcoids? - EquiManagement
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N-acetylcysteine protects against acyclovir-induced nephrotoxicity - News-Medical
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Antiviral therapy targets latent HSV infections - Nature
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ACICLOVIR EFFECT AS ANTIFUNGAL ADJUVANTED ON FUNGI ISOLATED FROM PATIENTS WITH KERATITIS - ARVO Journals
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Comparison of the Efficacy of Valacyclovir vs Acyclovir for the Prevention of Recurrent Herpes Simplex Virus Eye Disease | IOVS | ARVO Journals - ARVO Journals
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FDA OKs Acyclovir Ophthalmic Ointment - Pharmacy Times
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Dear Doctor: Is it true that antivirals like acyclovir may help prevent Alzheimer's? - OregonLive.com
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A Controlled Trial of Acyclovir for Chickenpox in Normal Children - NEJM
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Acyclovir: A Decade Later - NEJM
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Encephalopathy Induced by Preventive Administration of Acyclovir in a | IJGM - Dove Medical Press
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Long-Term Administration of Valacyclovir Reduces the Number of Epstein-Barr Virus (EBV)-Infected B Cells but Not the Number of EBV DNA Copies per B Cell in Healthy Volunteers - journals.asm.org
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A Controlled Trial Comparing Vidarabine with Acyclovir in Neonatal Herpes Simplex Virus Infection - NEJM
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Delayed Temporal Lobe Hemorrhage After Initiation of Acyclovir in an Immunocompetent Patient with Herpes Simplex Virus-2 Encephalitis: A Case Report - Cureus
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Thrombocytopenia Secondary to Herpes Simplex Virus-2 Infection Successfully Treated by Acyclovir - Cureus
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Helicase–Primase Inhibitor Pritelivir for HSV-2 Infection - NEJM
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Orthogonal Linking of Gemcitabine by Acyclovir and Bortezomib: A Rational Chemistry Laboratory Introduction of Both Noncovalent and Covalent Dynamics - ACS Publications
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Shingles treatment: Does alcohol use affect therapy? - Mayo Clinic
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Treating HSK Long Term - Review of Optometry
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Steroid, Antiviral Combo Most Effective for Herpes Stromal Keratitis - Review of Optometry
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The Elegance of Virology: How Acyclovir Slows Down Herpes. - American Council on Science and Health
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Acyclovir with Steroids to Restore Sudden Hearing Loss | Newswise - Newswise
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Acute renal failure related to topical acyclovir - Clinical Advisor
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Neonatal Herpes: Oral Acyclovir Improves Neurodevelopment - MDEdge
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Meet the woman who gave the world antiviral drugs - National Geographic
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Tonic-clonic seizure following combined treatment of mycophenolate mofetil and acyclovir - Springer Nature Link
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Determination of Acyclovir and Parabens Using HPLC in Different Pharmaceutical Formulations - Springer Nature Link
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Orals Only for Acute HSV? - Review of Optometry
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A Controlled Trial Comparing Foscarnet with Vidarabine for Acyclovir-Resistant Mucocutaneous Herpes Simplex in the Acquired Immunodeficiency Syndrome - NEJM
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Herpes Drugs Work, but Not Forever - MedPage Today
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Population Pharmacokinetics of Intravenous Acyclovir in Oncologic Pediatric Patients - Frontiers
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Stop an Antiviral for Vaccine? - Review of Optometry
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Successful Treatment with Foscarnet of an Acyclovir-Resistant Mucocutaneous Infection with Herpes Simplex Virus in a Patient with Acquired Immunodeficiency Syndrome - NEJM
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Herpes simplex virus reactivation among hematopoietic stem cell transplant recipients: re-evaluating acyclovir dosage - Nature
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HSVK Reoccurrence and Risk of Resistance - Review of Optometry
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Once-Daily Valacyclovir to Reduce the Risk of Transmission of Genital Herpes - NEJM
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Hypertrophic herpes simplex virus 2 infection resistant to acyclovir in an immunosuppressed patient - CMAJ | Journal
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Exploring the role of oral valacyclovir in the treatment of herpes simplex encephalitis - Healio
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Drug for rare disorder shows promise for treating herpes viruses - Medical Xpress
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Acyclovir-induced nephrotoxicity: Protective potential of N-acetylcysteine - EurekAlert!
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.