Why is "APOD (gene)" trending?
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Trend Analysis
- Ranking position: #
- Date: 2026-03-13 22:04:44
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
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Wikipedia Overview
Apolipoprotein D (ApoD) is a protein that in humans is encoded by the APOD gene. Unlike other lipoproteins, which are mainly produced in the liver, apolipoprotein D is mainly produced in the brain and testes. It is a 29 kDa glycoprotein discovered in 1963 as a component of the high-density lipoprotein (HDL) fraction of human plasma. It is the major component of human mammary cyst fluid. The human gene encoding it was cloned in 1986 and the deduced protein sequence revealed that ApoD is a member of the lipocalin family, small hydrophobic molecule transporters. ApoD is 169 amino acids long, including a secretion peptide signal of 20 amino acids. It contains two glycosylation sites and the molecular weight of the mature protein varies from 20 to 32 kDa.
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Search Interest Perspective
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Flu Severity in Older Adults Mediated by ApoD Regulation of Innate Antiviral Immunity - Genetic Engineering and Biotechnology News
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Downregulated APOD and FCGR2A correlates with immune infiltration and lipid-induced symptoms of irritable bowel syndrome - Nature
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Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila - PNAS
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2024 January 17 - America and the Sea of Serenity - NASA (.gov)
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The Lipocalin Apolipoprotein D Functional Portrait: A Systematic Review - Frontiers
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Astrocyte-derived apolipoprotein D is required for neuronal survival in Parkinson’s disease - Nature
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2014 March 15 - Apollo 17 VIP Site Anaglyph - NASA (.gov)
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Molecular Medicine Reports - Spandidos Publications
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Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis - Nature
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2020 January 17 - Apollo 17: A Stereo View from Lunar Orbit - NASA (.gov)
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Glioma facilitates the epileptic and tumor-suppressive gene expressions in the surrounding region - Nature
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A simple method using CRISPR-Cas9 to knock-out genes in murine cancerous cell lines - Nature
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Meta-signature of human endometrial receptivity: a meta-analysis and validation study of transcriptomic biomarkers - Nature
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Single-cell analysis of pancreatic ductal adenocarcinoma identifies a novel fibroblast subtype associated with poor prognosis but better immunotherapy response - Nature
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January 15, 1998 - Eugene Shoemaker: 1928-1997 - NASA (.gov)
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