Why is "5-alpha-reductase" trending?

Search Interest Perspective

• 5-α-reductase inhibitors and the risk of suicide and neuropsychiatric symptoms: a meta-analysis of observational studies - Frontiers
• 5α-Reductase underscores the development of pectoral fin breeding tubercles in zebrafish - Nature
• Cardiovascular Outcomes with α1 Adrenergic Receptor Antagonists vs 5α-Reductase Inhibitors - medRxiv
• IPSS advantage of 4.6 points favors Rezūm over alpha blocker plus 5-ARI - Urology Times
• Alopecia Treatment Not Tied to Bone Loss in Women - Medscape
• Two Hair Loss Drugs Not Tied to Heart Disease Risk - Medscape
• A proprietary lipidosterolic extract of Serenoa repens promotes hair growth through mechanisms that extend beyond 5-alpha reductase inhibition: Insights from human hair follicle organ culture - Wiley Online Library
• Integrative and Analytical Review of the 5-Alpha-Reductase Type 2 Deficiency Worldwide - Dove Medical Press
• Cardiovascular Risks Higher With Alpha Blocker vs 5-ARI Use in BPH - Renal and Urology News
• Paternity by Intrauterine Insemination with Sperm from a Man with 5α-Reductase-2 Deficiency - The New England Journal of Medicine
• Early embryonic exposure of freshwater gastropods to pharmaceutical 5-alpha-reductase inhibitors results in a surprising open-coiled “banana-shaped” shell - Nature
• Depression risk of 5-alpha reductase inhibitors: A systematic review and meta-analysis with a focus on comparator groups - medRxiv
• Is DHT Production by 5α-Reductase Friend or Foe in Prostate Cancer? - Frontiers
• 5‐Alpha‐Reductase 2 Deficiency in a Woman with Primary Amenorrhea - Wiley Online Library
• Cloning, computational analysis and expression profiling of steroid 5 alpha-reductase 1 (SRD5A1) gene during reproductive phases and ovatide stimulation in endangered catfish, Clarias magur - Nature
• Purple corn extract improves benign prostatic hyperplasia by inhibiting 5 alpha-reductase type 2 and inflammation in testosterone propionate-induced rats - Frontiers
• Caffeic acid N -[3,5-bis(trifluoromethyl)phenyl] amide as a non-steroidal inhibitor for steroid 5α-reductase type 1 using a human keratinocyte cell-based assay and molecular dynamics - Nature
• Suppression of steroid 5α-reductase type I promotes cellular apoptosis and autophagy via PI3K/Akt/mTOR pathway in multiple myeloma - Nature
• 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder | Neuropsychopharmacology - Nature
• Efficacy and tolerability of the dual 5α-reductase inhibitor, dutasteride, in the treatment of benign prostatic hyperplasia in African-American men | Prostate Cancer and Prostatic Diseases - Nature
• The Neurosteroidogenic Enzyme 5α -Reductase Mediates Psychotic-Like Complications of Sleep Deprivation - Nature
• The Molecular Basis of Steroid 5α-Reductase Deficiency in a Large Dominican Kindred - The New England Journal of Medicine
• The Diabetic Risks of 5-alpha Reductase Inhibitor Exposure - Diabetes In Control
• The Risks and Benefits of 5α-Reductase Inhibitors for Prostate-Cancer Prevention - The New England Journal of Medicine
• 5-ARIs Do Not Increase Prostate Cancer Mortality - Renal and Urology News
• Common BPH medications raise cardiac failure risk - Urology Times
• Human castration resistant prostate cancer rather prefer to decreased 5α-reductase activity - Nature
• Differential expression of androgen receptor and 5-α reductase isoforms in skin cells - Springer Nature Link
• Investigators: Consider 5-ARI Use When Deciding on Prostate Biopsy - Renal and Urology News
• Prostate Cancer Mortality and 5-ARI Use - ascopost.com
• Cinnamomi Cortex ( Cinnamomum verum ) Suppresses Testosterone-induced Benign Prostatic Hyperplasia by Regulating 5α-reductase - Nature
• Novel compound heterozygous mutations in the SRD5A2 gene from 46,XY infants with ambiguous external genitalia - Nature
• The Effect of 5 α‐Reductase Inhibitors on Erectile Function - Canguven - 2008 - Journal of Andrology - Wiley Online Library
• Pharmacological effects of saw palmetto extract in the lower urinary tract | Acta Pharmacologica Sinica - Nature
• Use of 5‐alpha reductase inhibitors and risk of gastrointestinal cancers in men with benign prostatic hyperplasia: A population‐based cohort study - Wiley Online Library
• Data cast light on ED/5-ARI connection - Urology Times
• 5α-Reductase inhibition does not adversely affect muscle mass - Nature
• Suicidal risk associated with finasteride versus dutasteride among men treated for benign prostatic hyperplasia: nationwide cohort study - Nature
• Figure 5. [Conversion of testosterone to dihydrotestosterone (DHT) by 5alpha reductase]. - Endotext - National Institutes of Health (NIH) | (.gov)
• Pao Pereira Extract Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats by inhibiting 5α-Reductase - Nature
• Caster Semenya accuses IAAF of using her as a ‘guinea pig experiment’ - The Guardian
• Taking 5-ARIs for BPH is not associated with increased mortality in prostate cancer - Karolinska Institutet
• 5α-reductase inhibitors linked to depression, but not dementia - Medical Xpress
• Risks, Safety, Danger, Side Effects Of 5 Alpha Reductase Inhibitors For Conventional Prostate Treatment (Part 1) - Modern Ghana
• Pharmacological Approaches in Managing Symptomatic Relief of Benign Prostatic Hyperplasia: A Comprehensive Review - Cureus
• The extraordinary case of the Guevedoces - BBC
• Compensatory mechanisms that maintain androgen production in mice lacking key androgen biosynthetic enzymes - Wiley & Sons
• Male and Female Pattern Hair Loss: A Guide to Treatment - Cleveland Clinic
• Dihydrotestosterone synthesis pathways from inactive androgen 5α-androstane-3β,17β-diol in prostate cancer cells: Inhibition of intratumoural 3β-hydroxysteroid dehydrogenase activities by abiraterone - Nature
• Androgens and the Evolution of Male-Gender Identity among Male Pseudohermaphrodites with 5α-Reductase Deficiency - The New England Journal of Medicine
• Real-world 5-ARI data show increased sexual side effects with finasteride vs dutasteride - Urology Times
• Healthy aging for him: Natural ingredients tackle men’s health issues - Nutritional Outlook
• Saw Palmetto Extract Ameliorates Benign Prostatic Hyperplasia by Regulating 5α-Reductase and Apoptosis In Vitro and In Vivo - Wiley Online Library
• 2 drugs for enlarged prostate not different in depression risk - Korea Biomedical Review
• 'Guevedoces': Rare Medical Condition Hides Child's Sex Until Age 12 - Live Science
• In This Remote Village, Some Boys Don't Grow a Penis Until They're 12 - ScienceAlert
• Blockade of Androgen Markers Using a Novel Betasitosterol, Thioctic Acid and Carnitine-containing Compound in Prostate and Hair Follicle Cell-based Assays - Wiley Online Library
• Reducing the risk of type 2 diabetes in men with benign prostatic hyperplasia—old steroids, new tricks - BMJ Blogs
• Imane Khelif, the IOC, World Boxing and mandatory sex testing - 3 Wire Sports
• World Boxing enacts sex-testing policy as Olympian Imane Khelif is set to compete - USA Today
• Brain 5α-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation - PNAS
• The Efficacy of Terazosin, Finasteride, or Both in Benign Prostatic Hyperplasia - The New England Journal of Medicine
• Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes - PNAS
• Complete NMR assignment and absolute configuration of k4610422, a norditerpenoid inhibitor of testosterone-5α-reductase originally from Streptosporangium : rediscovery from a thermophilic Actinomadura - Nature
• New insights into 5α-reductase type 2 deficiency based on a multi-centre study: regional distribution and genotype–phenotype profiling of SRD5A2 in 190 Chinese patients (Contributed by Baoheng Gui and Prof. Chunxiu Gong) - BMJ Blogs
• FDA Warns of High-Grade Prostate Ca Risk With BPH Drugs - MedPage Today
• Establishment and characterization of matched immortalized human frontal and occipital scalp dermal papilla cell lines from androgenetic alopecia - Nature
• Caster Semenya Q&A: Who is she and why is her case important? - BBC
• The Androgen 5α-Dihydrotestosterone and Its Metabolite 5α-Androstan-3β, 17β-Diol Inhibit the Hypothalamo–Pituitary–Adrenal Response to Stress by Acting through Estrogen Receptor β-Expressing Neurons in the Hypothalamus - Journal of Neuroscience
• 5-alpha-reductase inhibitors use tied to lower risk of COVID-19: Study - Medical Dialogues
• FDA Approves Addition to Cialis Labeling - empr.com
• Does saw palmetto treat hair loss? Use, side effects, and alternatives - Medical News Today
• 5-alpha-steroid reductase deficiency Archives - Sports Integrity Initiative
• Biosynthesis of 11KT and 11KDHT from the adrenal androgen precursor 11OHA4. - PLOS
• 'Imane Khelif a real woman', says USIM professor - NST Online
• Dutasteride (Avodart) Sexual Side Effects Can Be Daunting - The People's Pharmacy
• Imane Khelif, Olympic gold medallist, identified as 'man' with internal testicles in leaked report - Firstpost
• Who is Paris Olympics gold medalist Imane Khelif and what's the controversy with the leaked medical repor - The Times of India
• 7 expert-approved foods that can help reduce hair loss: Turmeric, onions and more - Vogue India
• Korea one of the first countries to issue warnings on finasteride - Korea Biomedical Review
• The ‘girls’ who grow penises at the age of 12 - PinkNews
• Las Salinas, The Village Where Girls Become Boys - The Guardian Nigeria News
• Imane Khelif Has 5-Alpha Reductase Deficiency? Boxer's 'Leaked Medical Report' Sparks Outrage - Times Now
• Imane Khelif confirmed biological men in leaked medical reports? - Jang
• Algerian Boxer Imane Khelif Has XY Chromosomes And "Testicles" : French-Algerian Medical Report Admits - reduxx.info