Why is "3-Iodothyronamine" trending?
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Trend Analysis
- Ranking position: #
- Date: 2026-03-13 18:27:09
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
This topic is not currently in the ranking.
Wikipedia Overview
3-Iodothyronamine (T1AM) is an endogenous thyronamine. It is a high-affinity ligand of the trace amine-associated receptor 1 (TAAR1). T1AM is the most potent endogenous TAAR1 agonist yet discovered. It is also an agonist of the TAAR2 and TAAR5 with similar potency as for the TAAR1 (all in the case of the human proteins). T1AM is not a ligand of the thyroid hormone receptors. However, it is additionally a ligand of various monoamine and other receptors. For instance, it is a muscarinic acetylcholine receptor antagonist.
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Trending Topic Today
Search Interest Perspective
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Substantial impact of 3-iodothyronamine (T1AM) on the regulations of fluorescent thermoprobe-measured cellular temperature and natriuretic peptide expression in cardiomyocytes - Nature
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Central Effects of 3-Iodothyronamine Reveal a Novel Role for Mitochondrial Monoamine Oxidases - Frontiers
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3-Iodothyronamine, a Novel Endogenous Modulator of Transient Receptor Potential Melastatin 8? - Frontiers
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Thyroid hormones derivatives reduce proliferation and induce cell death and DNA damage in ovarian cancer - Nature
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Similarities and Differences in the Peripheral Actions of Thyroid Hormones and Their Metabolites - Frontiers
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Thyroid Hormones, Thyromimetics and Their Metabolites in the Treatment of Liver Disease - Frontiers
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Commentary: Euthyroid Sick Syndrome in Patients With COVID-19 - Frontiers
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Nongenomic roles of thyroid hormones and their derivatives in adult brain: are these compounds putative neurotransmitters? - Frontiers
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The Case for TAAR1 as a Modulator of Central Nervous System Function - Frontiers
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.