Why is "3β-Hydroxyprogesterone" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-07-20 00:48:09
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
3β-Hydroxyprogesterone entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-07-20 and was most recently seen on 2026-07-20.
Wikipedia Overview
3β-Dihydroprogesterone (3β-DHP), also known as 3β-hydroxyprogesterone, or pregn-4-en-3β-ol-20-one, is an endogenous steroid. It is biosynthesized by 3β-hydroxysteroid dehydrogenase from progesterone. Unlike 3α-dihydroprogesterone (3α-DHP), 3β-DHP does not act as a positive allosteric modulator of the GABAA receptor, which is in accordance with the fact that other 3β-hydroxylated progesterone metabolites such as isopregnanolone and epipregnanolone similarly do not act as potentiators of this receptor and instead inhibit it as well as reverse the effects of potentiators like allopregnanolone. 3β-DHP has been reported to possess about the same potency as progesterone in a bioassay of progestogenic activity, whereas 3α-DHP was not assessed.
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Trending Topic Today
Search Interest Perspective
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Prevention of Recurrent Preterm Delivery by 17 Alpha-Hydroxyprogesterone Caproate - The New England Journal of Medicine
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Proluton Depot injection discontinued by Bayer - Springer Nature Link
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Establishing the Cut-Off Values of 17-Hydroxyprogesterone for Diagnosing Congenital Adrenal Hyperplasia: A Prospective Observational Study in a Tertiary Care Hospital - Cureus
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Candidate reference measurement procedure for serum 17-hydroxyprogesterone quantification via isotope dilution liquid chromatography–tandem mass spectrometry - Wiley Online Library
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Green method for 17-hydroxyprogesterone extraction and determination using PDMS stir bar sorptive extraction coupled with HPLC: optimization by response surface methodology - Nature
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11α- and 11β-Hydroxyprogesterone, Potent Inhibitors of 11β-Hydroxysteroid Dehydrogenase, Possess Hypertensinogenic Activity in the Rat - American Heart Association Journals
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FDA withdraws preterm birth drug Makena (hydroxyprogesterone) and its generic versions - Medical Dialogues
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A Trial of 17 Alpha-Hydroxyprogesterone Caproate to Prevent Prematurity in Twins - The New England Journal of Medicine
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OBGYN - Wiley & Sons
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.