Why is "2-Arachidonoylglycerol" trending?

Search Interest Perspective

• Unbiased assessment of 2-arachidonoylglycerol in cardiovascular inflammation - Nature
• ECNP 2025: Endocannabinoids have metabolic role in mental health - BioWorld MedTech
• The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles - PNAS
• Body’s Own Cannabinoids May Be Key to Reducing Excessive Fear Responses - news.feinberg.northwestern.edu
• 2-AG-Mediated Control of GABAergic Signaling Is Impaired in a Model of Epilepsy - Journal of Neuroscience
• 2-AG and anandamide enhance hippocampal long-term potentiation via suppression of inhibition - Frontiers
• In the quest for a TBI therapy, astrocytes may be the bull’s-eye - UT Health San Antonio
• Striatonigral direct pathway 2-arachidonoylglycerol contributes to ethanol effects on synaptic transmission and behavior - Nature
• 2-Arachidonoylglycerol Reduces Proteoglycans and Enhances Remyelination in a Progressive Model of Demyelination - Journal of Neuroscience
• Reactive spinal glia convert 2-AG to prostaglandins to drive aberrant astroglial calcium signaling - Frontiers
• Synapse type-independent degradation of the endocannabinoid 2-arachidonoylglycerol after retrograde synaptic suppression - PNAS
• Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects - Nature
• Subcellular Arrangement of Molecules for 2-Arachidonoyl-Glycerol-Mediated Retrograde Signaling and Its Physiological Contribution to Synaptic Modulation in the Striatum - Journal of Neuroscience
• Anandamide and 2-arachidonoylglycerol differentially modulate autistic-like traits in a genetic model of autism based on FMR1 deletion in rats - Nature
• 2-arachidonoylglycerol signaling impairs short-term fear extinction - Nature
• The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG - Nature
• mobilization and 2-arachidonoylglycerol release in rodent spinal cord astrocytes - Nature
• Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents - Nature
• Mobilization of endocannabinoids by midbrain dopamine neurons is required for the encoding of reward prediction - Nature
• Endocannabinoid-Mediated Control of Neural Circuit Excitability and Epileptic Seizures - Frontiers
• Modulation of the Endocannabinoid System as a Potential Anticancer Strategy - Frontiers
• Dietary fatty acid intake and gut microbiota determine circulating endocannabinoidome signaling beyond the effect of body fat | Scientific Reports - Nature
• Endocannabinoid signalling modulates susceptibility to traumatic stress exposure - Nature
• Regulation of adult neurogenesis by the endocannabinoid-producing enzyme diacylglycerol lipase alpha (DAGLa) - Nature
• For heavy drinkers, chronic pain associated with alcohol withdrawal could be permanent - Scripps Research
• Endocannabinoids Interact With the Dopaminergic System to Increase Sexual Motivation: Lessons From the Sexual Satiety Phenomenon - Frontiers
• Coordinated regulation of endocannabinoid-mediated retrograde synaptic suppression in the cerebellum by neuronal and astrocytic monoacylglycerol lipase - Nature
• Endocannabinoid signaling regulates the reinforcing and psychostimulant effects of ketamine in mice - Nature
• The endocannabinoid system: an overview - Frontiers
• Inhibition of Diacylglycerol Lipase Impairs Fear Extinction in Mice - Frontiers
• Brain monoglyceride lipase participating in endocannabinoid inactivation - PNAS
• Cannabinoid Receptor 2 Signaling in Neurodegenerative Disorders: From Pathogenesis to a Promising Therapeutic Target - Frontiers
• Editorial: The Emerging Role of Endocannabinoids in Synaptic Plasticity, Reward, and Addiction - Frontiers
• The major central endocannabinoid directly acts at GABAA receptors - PNAS
• Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum - Nature
• Enhanced endocannabinoid tone as a potential target of pharmacotherapy - ScienceDirect.com
• Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus - Nature
• The Endocannabinoid System and Oligodendrocytes in Health and Disease - Frontiers
• Could enhancing the body’s own marijuana-like chemical treat Alzheimer’s? - UT Health San Antonio
• Transient Cannabinoid Receptor 2 Blockade during Immunization Heightens Intensity and Breadth of Antigen-specific Antibody Responses in Young and Aged mice - Nature
• A new role for anandamide: defective link between the systemic and skin endocannabinoid systems in hypertrophic human wound healing - Nature
• Nord Stream 2 AG klagt gegen EU-Sanktionen - energate messenger
• Chronic Morphine Modulates the Contents of the Endocannabinoid, 2-Arachidonoyl Glycerol, in Rat Brain - Nature
• Membrane-mediated action of the endocannabinoid anandamide on membrane proteins: implications for understanding the receptor-independent mechanism - Nature
• Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake - PNAS
• Fatty Acid-Binding Protein 5 Modulates Brain Endocannabinoid Tone and Retrograde Signaling in the Striatum - Frontiers
• Biochemical and Proteomic Characterization of Recombinant Human α/β Hydrolase Domain 6 | Scientific Reports - Nature
• A collection of cannabinoid-related negative findings from autaptic hippocampal neurons - Nature
• Uncovering a Connection Between Cannabinoids and Migraine - The University of Arizona Health Sciences
• Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout ABHD12 Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype - Frontiers
• Effect of Monoacylglycerol Lipase Inhibition on Intestinal Permeability of Rats With Severe Acute Pancreatitis - Frontiers
• Sex-dimorphism in human serum endocannabinoid and n-acyl ethanolamine concentrations across the lifespan - Nature
• Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling - Nature
• Endocannabinoids: A Promising Impact for Traumatic Brain Injury - Frontiers
• Activation of PAF receptors results in enhanced synthesis of 2-arachidonoylglycerol (2-AG) in immune cells - Wiley
• Molecular Composition of the Endocannabinoid System at Glutamatergic Synapses - Journal of Neuroscience
• Long-Term Aberrations To Cerebellar Endocannabinoids Induced By Early-Life Stress - Nature
• Loss of Retrograde Endocannabinoid Signaling and Reduced Adult Neurogenesis in Diacylglycerol Lipase Knock-out Mice - Journal of Neuroscience
• Dynamic Change of Endocannabinoid Signaling in the Medial Prefrontal Cortex Controls the Development of Depression After Neuropathic Pain - Journal of Neuroscience
• Fatty-acid–binding protein 5 controls retrograde endocannabinoid signaling at central glutamate synapses - PNAS
• Ligands for cannabinoid receptors, promising anticancer agents - ScienceDirect.com
• Study Identifies a Signaling Molecule Involved in Resilience to Stress - Brain and Behavior Research
• Fine-tuning of synaptic upscaling at excitatory synapses by endocannabinoid signaling is mediated via the CB1 receptor - Nature
• The endocannabinoid system, anandamide and the regulation of mammalian cell apoptosis - Nature
• AP-4-mediated axonal transport controls endocannabinoid production in neurons - Nature
• GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils - Nature
• An endogenous cannabinoid (2-AG) is neuroprotective after brain injury - Nature
• colloidal nanocrystals with near-unity quantum yield for use in luminescent solar concentrators - Nature
• Sleep loss boosts hunger and high-calorie food choices - University of Chicago News
• Targeting a Brain Enzyme May Be the Key to Unlocking New Obesity Strategies - Genetic Engineering and Biotechnology News
• Extracellular vesicles released by microglia and macrophages carry endocannabinoids which foster oligodendrocyte differentiation - Frontiers
• Enantiomer-specific positive allosteric modulation of CB1 signaling in autaptic hippocampal neurons - ScienceDirect.com
• Effects of cannabinoids on ligand-gated ion channels - Frontiers
• Localization of Diacylglycerol Lipase-α around Postsynaptic Spine Suggests Close Proximity between Production Site of an Endocannabinoid, 2-Arachidonoyl-glycerol, and Presynaptic Cannabinoid CB1 Receptor - Journal of Neuroscience
• A novel crosstalk within the endocannabinoid system controls GABA transmission in the striatum - Nature
• Sleep loss boosts hunger and unhealthy food choices - UChicago Medicine
• Endocannabinoid Release Calms Epileptic Seizures but Also Leads to Adverse After-Effects - Genetic Engineering and Biotechnology News
• Correlating FAAH and anandamide cellular uptake inhibition using N-alkylcarbamate inhibitors: From ultrapotent to hyperpotent - ScienceDirect.com
• Nord Stream 2 AG gets more time for debt restructuring - Reuters
• The Endocannabinoid System and Spermatogenesis - Frontiers
• US announces sanctions on Nord Stream 2 - DW.com
• Metaplastic control of the endocannabinoid system at inhibitory synapses in hippocampus - PNAS
• Endocannabinoid Modulation of Predator Stress-Induced Long-Term Anxiety in Rats - Nature
• Blood Levels of the Endocannabinoid Anandamide are Increased in Anorexia Nervosa and in Binge-Eating Disorder, but not in Bulimia Nervosa - Nature
• /Ag nanowire with sputtered polytetrafluoroethylene film for high performance flexible heaters - Nature
• Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons - PNAS
• Retrograde endocannabinoid signaling at striatal synapses requires a regulated postsynaptic release step - PNAS
• Nord Stream 2 says it has not filed for insolvency - Reuters
• Brain’s THC equivalent can quell seizures but there’s a catch - futurity.org
• Mass spectrometry imaging of biomarker lipids for phagocytosis and signalling during focal cerebral ischaemia - Nature
• Nord Stream 2 AG and European energy companies sign financing agreements - Engie.com
• Identification and Functional Characterization of Brainstem Cannabinoid CB2 Receptors - Science | AAAS
• Nonpsychotropic Cannabinoid Receptors Regulate Microglial Cell Migration - Journal of Neuroscience
• Erratum: Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus - Nature
• Endocannabinoids in obesity: brewing up the perfect metabolic storm? - Wiley Online Library
• Activity-Dependent Modulation of Tonic GABA Currents by Endocannabinoids in Hirudo verbana - Frontiers
• Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins - PNAS
• The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors - Nature
• /Ag Aerogel and Its Photodegradation Performance in Gas Phase Formaldehyde - Nature
• A Reversible and Selective Inhibitor of Monoacylglycerol Lipase Ameliorates Multiple Sclerosis - Wiley Online Library