Why is "2,4,5-trichlorophenoxyacetic acid" trending?
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Trend Analysis
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- Date: 2026-03-13 18:17:24
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
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Wikipedia Overview
2,4,5-Trichlorophenoxyacetic acid, a synthetic auxin, is a chlorophenoxy acetic acid herbicide used to defoliate broad-leafed plants. It was developed in the late 1940s, synthesized by reaction of 2,4,5-trichlorophenol and chloroacetic acid. It was widely used in the agricultural industry until being phased out, starting in the late 1970s due to toxicity concerns. Agent Orange, a defoliant used by the British in the Malayan Emergency and the U.S. in the Vietnam War, was equal parts 2,4,5-T and 2,4-D. 2,4,5-T itself is toxic with a NOAEL of 3 mg/kg/day and a LOAEL of 10 mg/kg/day. Agent Pink contained 100% 2,4,5-T. Additionally, the manufacturing process for 2,4,5-T contaminates this chemical with trace amounts of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). TCDD is a carcinogenic persistent organic pollutant with long-term effects on the environment. With proper temperature control during production of 2,4,5-T, TCDD levels can be held to about 5 ppb. Before the TCDD risk was well understood, early production facilities lacked proper temperature controls and individual batches tested later were found to have as much as 60 ppm of TCDD.
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Search Interest Perspective
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A Town, a Flood, and Superfund: Looking Back at the Times Beach Disaster Nearly 40 Years Later - U.S. Environmental Protection Agency (.gov)
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Read "Post-Vietnam Dioxin Exposure in Agent Orange-Contaminated C-123 Aircraft" at NAP.edu - nationalacademies.org
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Science on the Cover: The Shadow of 'Agent Orange' Lingers Over Vietnam, 50 Years After War's End - 동아사이언스
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Is Agent Orange Still at Large? — Chromatography Investigates - Chromatography Today
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2,4-D: Concerns about cancer and other serious illnesses - U.S. Right to Know
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Exposures Increase DLBCL Risks for Veterans, Servicemembers - U.S. Medicine
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Agent Orange's Legacy - C&EN
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Children of Vietnam Veterans fight for victims of Agent Orange - PhillyBurbs
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Agent Orange linked to Alzheimer’s — and there’s good chance you’ve been exposed - StudyFinds
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Okinawa Dumpsite Offers Proof of Agent Orange: Experts Say 沖縄ゴミ捨て場から枯れ葉剤・エージェント・オレンジ検出 専門家主張 - Asia-Pacific Journal: Japan Focus
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Okinawa dump site may be proof of Agent Orange: experts - The Japan Times
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More soil sampling for Agent Orange - The Guam Daily Post
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DOW HALTS FIGHT TO SELL HERBICIDE (Published 1983) - The New York Times
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In the 1950s, the British used herbicides as a weapon against Malayan communists. - CILISOS
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Suit Alleges Monsanto Endangered Employes - The Washington Post
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UPL asked to explain how ‘Agent Orange’ war poison chemical ended up in Durban river - Daily Maverick
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Electricity utility to pay compensation over use of cancer-linked herbicide - Australian Broadcasting Corporation
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Taranaki farmer with terminal cancer fought two years to get compensation - RNZ
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