Why is "14-3-3 proteins" trending?

Search Interest Perspective

• A high-throughput screening approach to discover potential colorectal cancer chemotherapeutics: repurposing drugs to identify novel disruptors of 14-3-3 proteins | Cell Death & Disease - Nature
• Phosphorylation-dependent association of a bacterial effector with plant 14-3-3 proteins enhances effector stability and bacterial virulence - Wiley
• Encephalomyocarditis virus protein 2B* interacts with 14-3-3 proteins through a phosphorylated C-terminal binding motif - ASM Journals
• Uncovering the molecular details of the 14-3-3 recruitment by mutant Sod1 species - Nature
• The yeast 14-3-3 proteins Bmh1 and Bmh2 regulate key signaling pathways - Frontiers
• 14-3-3 Proteins: A Number of Functions for a Numbered Protein - Science | AAAS
• Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins - PNAS
• 14-3-3 binding maintains the Parkinson’s associated kinase LRRK2 in an inactive state - Nature
• 14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses - Wiley
• Structural basis of ubiquitin ligase Nedd4-2 autoinhibition and regulation by calcium and 14-3-3 proteins - Nature
• 14-3-3 proteins regulate photomorphogenesis by facilitating light-induced degradation of PIF3 - Wiley
• A clade of receptor-like cytoplasmic kinases and 14-3-3 proteins coordinate inositol hexaphosphate accumulation - Nature
• Versatility of 14-3-3 proteins and their roles in bone and joint-related diseases - Nature
• Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners - Nature
• 14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface - Nature
• Pathways to Parkinson’s disease: a spotlight on 14-3-3 proteins - Nature
• Calcium-activated 14-3-3 proteins as a molecular switch in salt stress tolerance - Nature
• Region-specific inhibition of 14-3-3 proteins induces psychomotor behaviors in mice - Nature
• The dynamic and stress-adaptive signaling hub of 14-3-3: emerging mechanisms of regulation and context-dependent protein–protein interactions - Nature
• Coat proteins of necroviruses target 14-3-3a to subvert MAPKKKα-mediated antiviral immunity in plants - Nature
• 14-3-3 Proteins: Hot numbers in signal transduction - ScienceDirect.com
• The Saccharomyces cerevisiae 14-3-3 proteins Bmh1 and Bmh2 directly influence the DNA damage-dependent functions of Rad53 - PNAS
• Regulation of starch accumulation by granule-associated plant 14-3-3 proteins - PNAS
• Inhibition of 14-3-3 Proteins Alters Neural Oscillations in Mice - Frontiers
• 14-3-3 signal adaptor and scaffold proteins mediate GPCR trafficking - Nature
• 14-3-3 Proteins Reduce Cell-to-Cell Transfer and Propagation of Pathogenic α-Synuclein - Journal of Neuroscience
• Differential neuroprotective effects of 14-3-3 proteins in models of Parkinson's disease - Nature
• 14-3-3 Proteins in Plant Hormone Signaling: Doing Several Things at Once - Frontiers
• Differential abundance and transcription of 14-3-3 proteins during vegetative growth and sexual reproduction in budding yeast - Nature
• Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins - PNAS
• Deciphering opening mechanisms of 14‐3‐3 proteins - Barrera - 2025 - Protein Science - Wiley Online Library
• 14-3-3 proteins act as intracellular receptors for rice Hd3a florigen - Nature
• Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR - Nature
• 14-3-3 Proteins regulate Akt Thr308 phosphorylation in intestinal epithelial cells - Nature
• Concatenation of 14-3-3 with partner phosphoproteins as a tool to study their interaction - Nature
• Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity - Nature
• Hierarchized phosphotarget binding by the seven human 14-3-3 isoforms - Nature
• Proteomics Profiling Reveals Carbohydrate Metabolic Enzymes and 14-3-3 Proteins Play Important Roles for Starch Accumulation during Cassava Root Tuberization - Nature
• Functions of OsBZR1 and 14-3-3 proteins in brassinosteroid signaling in rice - PNAS
• Covalent attachment of pyridoxal-phosphate derivatives to 14-3-3 proteins - PNAS
• Keratin binding to 14-3-3 proteins modulates keratin filaments and hepatocyte mitotic progression - PNAS
• 14-3-3 Proteins in Brain Development: Neurogenesis, Neuronal Migration and Neuromorphogenesis - Frontiers
• Down-regulation of 14-3-3ζ suppresses anchorage-independent growth of lung cancer cells through anoikis activation - PNAS
• 14-3-3 proteins—an update - Nature
• The subcortical maternal complex modulates the cell cycle during early mammalian embryogenesis via 14-3-3 - Nature
• 14-3-3 phosphoprotein interaction networks – does isoform diversity present functional interaction specification? - Frontiers
• Phosphorylation of Connexin36 near the C-terminus switches binding affinities for PDZ-domain and 14–3–3 proteins in vitro - Nature
• Crystal structure of potato 14-3-3 protein St14f revealed the importance of helix I in StFDL1 recognition - Nature
• Primate-specific isoform of Nedd4-1 regulates substrate binding via Ser/Thr phosphorylation and 14-3-3 binding - Nature
• On the role of residue phosphorylation in 14-3-3 partners: AANAT as a case study - Nature
• Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling - Nature
• A Cdc2-related protein kinase hPFTAIRE1 from human brain interacting with 14-3-3 proteins - Nature
• Structural basis for protein–protein interactions in the 14-3-3 protein family - PNAS
• 14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains - Nature
• 14-3-3 proteins in the nervous system - Nature
• 14-3-3ζ coordinates adipogenesis of visceral fat - Nature
• -dependent protein kinase CPK3 is required for sphingolipid-induced cell death in Arabidopsis - Nature
• Physiological and interactomic analysis reveals versatile functions of Arabidopsis 14-3-3 quadruple mutants in response to Fe deficiency - Nature
• Revealing the binding modes and the unbinding of 14-3-3σ proteins and inhibitors by computational methods - Nature
• Light-triggered and phosphorylation-dependent 14-3-3 association with NON-PHOTOTROPIC HYPOCOTYL 3 is required for hypocotyl phototropism - Nature
• The 14-3-3 protein GENERAL REGULATORY FACTOR11 (GRF11) acts downstream of nitric oxide to regulate iron acquisition in Arabidopsis thaliana - Wiley
• 14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function - Nature
• Regain flood adaptation in rice through a 14-3-3 protein OsGF14h - Nature
• G-protein-coupled receptors mediate 14-3-3 signal transduction - Nature
• Dynamic changes of the Prf/Pto tomato resistance complex following effector recognition - Nature
• Regulation of trehalase activity by multi-site phosphorylation and 14-3-3 interaction - Nature
• Dual engagement of 14-3-3 proteins controls signal relay from ASK2 to the ASK1 signalosome - Nature
• Controllability of protein-protein interaction phosphorylation-based networks: Participation of the hub 14-3-3 protein family - Nature
• α-Synuclein Shares Physical and Functional Homology with 14-3-3 Proteins - Journal of Neuroscience
• Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein–protein interactions - Nature
• JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage - Nature
• Disruption of melatonin synthesis is associated with impaired 14-3-3 and miR-451 levels in patients with autism spectrum disorders - Nature
• Structures of BRAF–MEK1–14-3-3 sheds light on drug discovery - Nature
• Phosphatidylinositol 4-kinase IIIβ (PI4KB) forms highly flexible heterocomplexes that include ACBD3, 14-3-3, and Rab11 proteins - Nature
• Neuroprotective Function of 14‐3‐3 Proteins in Neurodegeneration - Shimada - 2013 - BioMed Research International - Wiley Online Library
• 14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholamban - Science | AAAS
• Altered Expression of 14-3-3 Genes in the Prefrontal Cortex of Subjects with Schizophrenia - Nature
• p38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1 - Nature
• Alternative application of Tau protein in Creutzfeldt-Jakob disease diagnosis: Improvement for weakly positive 14-3-3 protein in the laboratory - Nature
• The 14-3-3 Brain Protein in Cerebrospinal Fluid as a Marker for Transmissible Spongiform Encephalopathies - New England Journal of Medicine
• The crystal structure of the non-liganded 14-3-3σ protein: insights into determinants of isoform specific ligand binding and dimerization - Nature
• A20 zinc finger protein inhibits TNF-induced apoptosis and stress response early in the signaling cascades and independently of binding to TRAF2 or 14-3-3 proteins - Nature
• Establishment of a standard 14-3-3 protein assay of cerebrospinal fluid as a diagnostic tool for Creutzfeldt–Jakob disease - Nature
• Seizure-like activity leads to the release of BAD from 14-3-3 protein and cell death in hippocampal neurons in vitro - Nature
• KGJN publication in "Molecular and Cellular Proteomics" - Universitetet i Bergen