Why is "Κ-Opioid receptor agonist" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-07-26 13:52:35
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Κ-Opioid_receptor_agonist entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-07-26 and was most recently seen on 2026-07-26.
Wikipedia Overview
A κ-opioid receptor agonist, or simply KOR agonist or kappa agonist, is a drug which acts as an agonist of the κ-opioid receptor (KOR), the target of the endogenous dynorphin peptides such as dynorphin A and one of several types of opioid receptors. They can variably produce hallucinogenic effects, pro-depressive and dysphoric effects, sedation, analgesic effects, antipruritic (anti-itch) effects, and anti-addictive effects, among others. Due to their various effects, KOR agonists are used for a variety of medical uses and for other purposes.
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Trending Topic Today
Search Interest Perspective
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Kappa opioid receptor control of motivated behavior revisited - Neuropsychopharmacology - Nature
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The translational potential of salvinorin A: systematic review and meta-analysis of preclinical studies - Nature
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Nalfurafine, a G-Protein–Biased KOR (Kappa Opioid Receptor) Agonist, Enhances the Diuretic Response and Limits Electrolyte Losses to Standard-of-Care Diuretics - American Heart Association Journals
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A Phase 3 Trial of Difelikefalin in Hemodialysis Patients with Pruritus - The New England Journal of Medicine
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Nucleus Accumbens μ-Opioid Receptors Mediate Social Reward - Journal of Neuroscience
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Effects of the novel selective κ-opioid receptor agonist NP-5497-KA on morphine-induced reward-related behaviors - Nature
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Eluxadoline for Irritable Bowel Syndrome with Diarrhea - The New England Journal of Medicine
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Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation - Nature
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A single, extinction-based treatment with a kappa opioid receptor agonist elicits a long-term reduction in cocaine relapse - Nature
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The atypical antidepressant and neurorestorative agent tianeptine is a μ-opioid receptor agonist - Nature
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In vivo photopharmacology with a caged mu opioid receptor agonist drives rapid changes in behavior - Nature
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Nalmefene Induced Elevation in Serum Prolactin in Normal Human Volunteers: Partial Kappa Opioid Agonist Activity? - Nature
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Direct Evidence for the Involvement of the Mesolimbic κ -Opioid System in the Morphine-Induced Rewarding Effect Under an Inflammatory Pain-Like State - Nature
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.